Gallixa: Sarcoid and Wound Care for Horses

Selected Scientific Publications About Gallium Maltolate

Scientific Articles on Gallium Maltolate for Horses


Shaw SD, Arroyo LG, zur Linden A, Allen C, Giraldo A, Cohen ND (2020) Medical management of a large intra‐abdominal mass caused by Rhodococcus equi in a foal. Equine Veterinary Education: doi:10.1111/eve.13389

Lawless SP, Cohen ND, Lawhon SD, Chamoun-Emanuelli AM, Wu J, Rivera-Vélez A, et al. (2020) Effect of gallium maltolate on a model of chronic, infected equine distal limb wounds. PLoS ONE 15(6): e0235006. https://doi.org/10.1371/journal.pone.0235006.

Cohen ND et al. (2015) Gallium maltolate as an alternative to macrolides for treatment of presumed Rhodococcus equi pneumonia in foals

Arnold CE et al. (2010) Pharmacokinetics of gallium maltolate after intragastric administration in adult horses

Chaffin MK et al. (2010) Pharmacokinetics of an orally-administered methylcellulose formulation of gallium maltolate in neonatal foals

Coleman M et al. (2010) In vitro antimicrobial activity of gallium maltolate against virulent Rhodococcus equi

Martens RJ et al. (2010) Pharmacokinetics of gallium maltolate after intragastric administration in neonatal foals

Martens RJ et al. (2010) Gallium maltolate: safety in neonatal foals following multiple enteral administrations

Martens RJ et al. (2007) Chemoprophylactic antimicrobial activity of gallium maltolate against intracellular Rhodococcus equi

Harrington JR et al. (2006) Antimicrobial activity of gallium against virulent Rhodococcus equi in vitro and in vivo

Martens RJ et al. (2006) Gallium therapy: a novel metal-based antimicrobial strategy for potential control of Rhodococcus equi foal pneumonia

General Scientific Articles on Gallium Maltolate


Fecteau M et al. (2014) Comparison of the antimicrobial activities of gallium nitrate and gallium maltolate against Mycobacterium avium subsp. paratuberculosis in vitro

Bernstein LR (2013) Gallium, therapeutic effects, in Encyclopedia of Metalloproteins, Kretsinger RH, Uversky VN, and Permyakov EA, eds., pp. 823-835, Springer, New York.

Arnold CE et al. (2012) Antimicrobial activity of gallium maltolate against Staphylococcus aureus and methicillin-resistant S. aureus and Staphylococcus pseudintermedius: An in vitro study

Bernstein LR (2011) Hepatocellular carcinoma detection by gallium scan and subsequent treatment by gallium maltolate: rationale and case study

DeLeon K et al. (2009) Gallium maltolate treatment eradicates Pseudomonas aeruginosa infection in thermally injured mice

Chitambar CR et al. (2007) Development of gallium compounds for treatment of lymphoma: gallium maltolate, a novel hydroxypyrone gallium compound, induces apoptosis and circumvents lymphoma cell resistance to gallium nitrate

Bernstein LR (2005) Therapeutic gallium compounds

Bernstein LR et al. (2000) Chemistry and pharmacokinetics of gallium maltolate, a compound with high oral gallium bioavailability

Bernstein LR (1998) Mechanisms of therapeutic activity for gallium

Topical Gallium Maltolate



Lawless SP, Cohen ND, Lawhon SD, Chamoun-Emanuelli AM, Wu J, Rivera-Vélez A, Weeks BR, Whitfield-Cargile CM (2020) Effect of gallium maltolate on a model of chronic, infected equine distal limb wounds. PLoS ONE 15(6): e0235006. https://doi.org/10.1371/journal.pone.0235006.

Cereceres S, Lan Z, Bryan L, Whitely M, Wilems T, Greer H, Alexander ER, Taylor RJ, Bernstein LR, Cohen N, Whitfield-Cargile C, Cosgriff-Hernandez E (2019) Bactericidal activity of 3D-printed hydrogel dressing loaded with gallium maltolate. APL Bioengineering 3, 026102; doi: 10.1063/1.5088801.

Giacani L, Bernstein LR, Haynes AM, Godornes BC, Ciccarese G, Drago F, Parodi A, Valdevit S, Anselmi L, Tomasini CF, Baca AM (2019) Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws. PLoS Neglected Tropical Diseases 13(1): e0007076.

Bernstein LR (2018) Topical gallium maltolate as a possible alternative to opioids in the treatment of chronic pain. 17th World Congress on Pain, Boston, Massachusetts, 16 September 2018.

Hummig W, Neto JS, Benzecry de Almeida D, Bernstein LR (2016) Efficacy of topical gallium maltolate for neuropathic orofacial pain following surgery or radiotherapy. 16th World Congress on Pain, Yokohama, Japan, 27 September, 2016.

Bernstein LR (2014) Successful treatment of refractory trigeminal neuralgia with topical gallium maltolate. 15th World Congress on Pain, Buenos Aires, Argentina, 10 October, 2014.

Bernstein LR (2013) Gallium maltolate: a new topical analgesic agent. 4th International Congress on Neuropathic Pain, Toronto, Canada, 23-26 May, 2013.

Bernstein LR (2012) Successful treatment of refractory postherpetic neuralgia with topical gallium maltolate: Case report. Pain Medicine 13:915-918.

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